Actively Recruiting

Age: 18Years +
All Genders
NCT05551416

The EpiGASTRIC/EDGAR Project: New Strategies for the Early Detection and Prevention of Gastric Cancer

Led by EDUARDO ALBENIZ · Updated on 2023-10-24

1200

Participants Needed

15

Research Sites

277 weeks

Total Duration

On this page

Sponsors

E

EDUARDO ALBENIZ

Lead Sponsor

I

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is a multicenter, prospective cohort study, which are planned to enroll at least 600 patients who diagnosed the primary gastric cancer (GC); around 50 patients with premalignant gastric lesions (PGLs) and early gastric neoplasias (EGC) treated by endoscopy resection; and no less than 600 healthy normal cohort participants, for more than 18 months in the Spanish population. All participants who enrolled in this registry will be questioned by the life habits survey; and clinical data and biological samples of these participants were analyzed in order to look for new diagnostic tools. The aim of this study is to evaluate clinical, endoscopic and molecular approaches to identify individuals with high-risk of GC. Thus, it would be allow the adoption of preventive measures to reduce mortality through early detection and/or the reduction of its incidence.

CONDITIONS

Official Title

The EpiGASTRIC/EDGAR Project: New Strategies for the Early Detection and Prevention of Gastric Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults over 18 years-old.
  • Symptomatic patients undergoing diagnostic gastroscopy for prevalence study of premalignant gastric lesions.
  • Patients with premalignant gastric lesions and early gastric cancer indicated for endoscopic resection.
  • Patients diagnosed with gastric cancer.
  • Controls without gastric pathology or family history of gastric cancer, from EDGAR 1 cohort.
Not Eligible

You will not qualify if you...

  • Patient refuses to participate in the study.
  • Medical, psychological, or legal inability to enter the study.
  • For EDGAR 1: previous diagnosis of premalignant gastric lesions, previous gastric surgery, contraindication for gastroscopy or biopsies.
  • For EDGAR 2: contraindication for resection or biopsy.
  • For EPIGASTRIC: gastric neoplasm other than adenocarcinoma.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 15 locations

1

Hospital Comarcal de Inca

Palma de Mallorca, Balearic Islands, Spain

Actively Recruiting

2

Hospital de Llevant

Porto Cristo, Balearic Islands, Spain

Actively Recruiting

3

Hospital General de Granollers

Granollers, Barcelona, Spain

Actively Recruiting

4

Consorci Sanitari de Terrassa

Terrassa, Barcelona, Spain

Actively Recruiting

5

Hospital Santos Reyes

Aranda de Duero, Burgos, Spain

Actively Recruiting

6

Hospital de Mérida

Mérida, Extremadura, Spain

Actively Recruiting

7

Hospital Universitario de Ourense

Ourense, Galicia, Spain

Actively Recruiting

8

Hospital Puerta de Hierro

Majadahonda, Madrid, Spain

Actively Recruiting

9

Hospital Universitario de Navarra

Pamplona, Navarre, Spain

Actively Recruiting

10

Hospital Universitario Central de Asturias

Oviedo, Principality of Asturias, Spain

Actively Recruiting

11

Hospital Clínic de Barcelona

Barcelona, Spain

Actively Recruiting

12

Hospital Universitario de Burgos

Burgos, Spain

Actively Recruiting

13

Hospital Josep Trueta

Girona, Spain

Actively Recruiting

14

Hospital Clínico Universitario Lozano Blesa

Zaragoza, Spain

Actively Recruiting

15

Hospital Universitario Miguel Servet

Zaragoza, Spain

Actively Recruiting

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Research Team

L

Leticia Moreira, MD, PhD

CONTACT

E

Eduardo Albéniz, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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