Actively Recruiting

Age: 20Years +
All Genders
NCT06838806

Epigenetic Nucleosomes in Plasma for Pulmonary Nodule Differentiation

Led by National Taiwan University Hospital · Updated on 2025-11-19

500

Participants Needed

1

Research Sites

55 weeks

Total Duration

On this page

Sponsors

N

National Taiwan University Hospital

Lead Sponsor

V

Volition Diagnostics UK Ltd

Collaborating Sponsor

AI-Summary

What this Trial Is About

Investigators aim to evaluate the diagnostic accuracy of the Nu.Q blood test for lung cancer in the Taiwanese population and compare its diagnostic performance with low-dose computed tomography (LDCT) or computed tomography (CT). Additionally, investigators will investigate the potential role of Nu.Q in lung cancer prevention and its impact on survival outcomes. Study Method: Investigators plan to collect 20 mL of blood samples from individuals undergoing chest LDCT/CT, isolate plasma for Nu.Q™ analysis, and compare the results with corresponding lung cancer pathology findings. The estimated sample size is 500 participants.

CONDITIONS

Official Title

Epigenetic Nucleosomes in Plasma for Pulmonary Nodule Differentiation

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 20 or older
  • Underwent a low-dose chest CT scan or a standard chest CT scan showing lung nodules 6 mm or larger
  • Understand the consent form and agree to participate in the study
  • Lung nodules assessed by a physician as high-risk and requiring thoracic surgery or biopsy for diagnosis
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Unable to understand consent or unwilling to participate
  • Assessed by a physician as unsuitable for thoracic surgery or biopsy for diagnosis

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

National Taiwan University

Taipei, Taiwan

Actively Recruiting

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Research Team

P

Pei-Hsing Chen, MD

CONTACT

J

Jin-Shing Chen, M.D., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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