Actively Recruiting

All Genders
NCT07205666

The Eplontersen Pregnancy and Lactation Outcomes Study

Led by AstraZeneca · Updated on 2026-05-01

10

Participants Needed

1

Research Sites

526 weeks

Total Duration

On this page

Sponsors

A

AstraZeneca

Lead Sponsor

I

ICON plc

Collaborating Sponsor

AI-Summary

What this Trial Is About

The overall objective of this DPSS is to describe the occurrence of pregnancy and maternal complications, adverse effects on the developing fetus and neonate, and adverse effects on the infant associated with exposure to eplontersen during pregnancy and/or lactation.

CONDITIONS

Official Title

The Eplontersen Pregnancy and Lactation Outcomes Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnancy and/or lactation cases with exposure to eplontersen and a diagnosis of an approved indication for treatment with eplontersen
  • Adverse event reports in infants under 12 months of age linked to pregnancy or lactation exposure to eplontersen in individuals diagnosed with an approved indication
Not Eligible

You will not qualify if you...

  • Case reports lacking minimum data at first report and follow-up
  • Cases where the reporter does not wish to be contacted for follow-up
  • Cases where the reporter or patient cannot be identified

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Research Site

Frankfurt, Germany

Actively Recruiting

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Research Team

A

AstraZeneca Clinical Study Information Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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