A Short, Four-Session Cognitive Behavioral Therapy for Urologic Chronic Pelvic Pain Syndrome UCPPS and Related Conditions

What this Trial Is About

Researchers are studying a brief cognitive behavioral therapy CBT program designed to reduce symptoms of urologic chronic pelvic pain syndrome UCPPS, which includes conditions like interstitial cystitisbladder pain syndrome and chronic prostatitis. This research explores a shorter, 4-session transdiagnostic behavioral treatment that may be easier for patients, providers, and payers to use compared to longer traditional therapies. The study also aims to understand how this therapy works and who benefits most, especially given the high costs and widespread impact of related chronic pain conditions. Participants will be randomly assigned to receive either a minimal contact CBT involving four sessions focused on teaching self-management skills for pelvic pain and urinary symptoms or a four-session educationsupport program providing science-based information and therapeutic support. Both treatments are largely home-based with minimal therapist contact. The study measures treatment effects at baseline, after 12 weeks, and at 3- and 6-month follow-ups to assess symptom improvements and treatment durability. During the study, participants will complete various assessments including symptom diaries, validated questionnaires for pain and psychological symptoms, and satisfaction surveys. The primary outcome is the Clinical Global Impressions Improvement Scale measured 12 weeks after baseline. Researchers also evaluate secondary outcomes like pain impact, symptom severity, and psychological distress. Follow-up assessments occur up to 6 months post-treatment to monitor ongoing effects and participant progress over time.

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program