Actively Recruiting
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
Led by State University of New York at Buffalo · Updated on 2026-01-26
240
Participants Needed
3
Research Sites
311 weeks
Total Duration
On this page
Sponsors
S
State University of New York at Buffalo
Lead Sponsor
U
University of California, Los Angeles
Collaborating Sponsor
AI-Summary
What this Trial Is About
The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with clinical and practical advantages over existing behavioral therapies whose length and focus limits their adoption by clinicians and coverage for mechanistically similar comorbidities. A theoretically informed, practical, empirically grounded approach will systematically unpack CBT's working mechanisms, clarify for whom it works, ease dissemination, appeal to patients, providers, payers, and policy makers in the COVID-19 era favoring low resource intensity treatments, and reduce cost and inefficiencies associated with high intensity therapies whose complexity, length, and scarcity restricts uptake and impact.
CONDITIONS
Official Title
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18-70 years inclusive
- Male or female, all genders, races, and ethnic groups
- Diagnosed by a doctor with interstitial cystitis/bladder pain syndrome or chronic prostatitis/chronic pelvic pain syndrome
- Pelvic pain or uncomfortable pressure lasting at least six months
- Pelvic pain with moderate severity (3 or greater on a 0-10 scale) causing weekly life interference
- Ability to understand and provide informed consent
- Not starting new medications during the 2-week pre-treatment baseline unless medically necessary
- Minimum 6th grade reading level
- Willing to be randomized to either CBT or education/support and follow assigned protocol
- Willing to be contacted for follow-up assessments at 12 weeks, 3 months, and 6 months post-treatment
- Willing to attend sessions
- Able to maintain symptom diaries and complete paperwork
- Access to telephone and computer or smartphone
- Willing and able to provide adequate contact information
You will not qualify if you...
- Neurological conditions affecting the bladder (e.g., MS, Parkinson's disease, paraplegia)
- Symptomatic urethral stricture (males only)
- History of cystitis caused by tuberculosis, radiation, or chemotherapy
- Diagnosed and treated for pelvic-related cancers (colon, bladder, prostate, ovarian, endometrial, uterine, testicular, penile, cervical, vaginal, or rectal cancer)
- Medical conditions that are unstable, life threatening, or may interfere with study conduct or safety
- Severe cognitive impairment, deafness, blindness, or severe vision or hearing problems
- Major psychiatric disorders that would impede study participation (e.g., major depression with high suicide risk, recent substance abuse, schizophrenia)
- Currently receiving psychotherapy specifically for urological symptoms
- Schedule conflicts preventing participation, including plans to move or lack of transportation
- Inability to complete the study protocol
- Unable to read or fluently speak English
- Unable to complete screening visits
- Inaccessible for interventions or follow-up evaluations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
UCLA
Los Angeles, California, United States, 90095-7378
Active, Not Recruiting
2
University of Michigan
Ann Arbor, Michigan, United States, 48109-5330
Active, Not Recruiting
3
University at Buffalo (the only clinical site where treatment is delivered)
Buffalo, New York, United States, 14215
Actively Recruiting
Research Team
J
Jeffrey Lackner, PsyD
CONTACT
P
Patricia O'Leary, EdM
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here