Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07336160

ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty

Led by Nermin Ocaktan · Updated on 2026-01-14

72

Participants Needed

1

Research Sites

35 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this randomized controlled study is to investigate the effect of implementing a preoperative nutrition education and fasting protocol prepared in accordance with Enhanced Recovery After Surgery (ERAS) guidelines during the 24-hour preoperative period on postoperative hydration status and the incidence of nausea and vomiting in patients scheduled for total knee arthroplasty. Total knee arthroplasty is a commonly performed surgical procedure, particularly in older adults, and postoperative recovery may be negatively affected by surgical stress, anesthesia-related complications, dehydration, and postoperative nausea and vomiting. ERAS protocols emphasize the optimization of preoperative nutrition and hydration as key components to improve postoperative outcomes. In this study, patients undergoing elective total knee arthroplasty will be randomly assigned to an intervention group or a control group. Patients in the intervention group will receive ERAS-based preoperative nutrition education and a standardized fasting protocol during the 24 hours prior to surgery, while patients in the control group will receive routine standard care. Postoperative hydration status, nausea and vomiting severity, and fluid intake-output balance will be assessed and compared between the two groups. The findings of this study are expected to contribute to improving perioperative nursing care practices and enhancing patient recovery and comfort following total knee arthroplasty.

CONDITIONS

Official Title

ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years and older.
  • Patients scheduled for elective total knee arthroplasty.
  • Patients expected to be hospitalized for at least 48 hours postoperatively.
  • Ability to communicate verbally and provide informed consent.
  • Patients with adequate cognitive and neurological capacity to understand study procedures.
Not Eligible

You will not qualify if you...

  • Presence of any chronic disease requiring fluid restriction.
  • Diagnosed cognitive impairment or psychiatric disorders affecting comprehension (e.g., Alzheimer's disease, dementia, psychotic disorders).
  • Acute conditions causing dehydration in the preoperative period (e.g., vomiting, diarrhea, excessive fluid loss).
  • Intraoperative complications requiring intensive care unit admission.
  • Postoperative follow-up shorter than 48 hours due to early discharge or transfer to another clinic.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Acıbadem Health Group Atakent Hospital

Istanbul, Istanbul, Turkey (Türkiye), 34752

Actively Recruiting

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Research Team

N

Nermin Ocaktan, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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