Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07336160

Effect of ERAS-Based Preoperative Nutrition Education and Fasting Protocol on Postoperative Hydration and Nausea in Total Knee Arthroplasty

Led by Nermin Ocaktan · Updated on 2026-01-14

72

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how following a preoperative nutrition education and fasting protocol based on Enhanced Recovery After Surgery (ERAS) guidelines affects postoperative hydration and the occurrence of nausea and vomiting in patients having total knee arthroplasty. Total knee arthroplasty is a common surgery, especially in older adults, where recovery can be complicated by surgical stress, anesthesia issues, dehydration, and nausea. Optimizing nutrition and hydration before surgery may improve these outcomes. Participants will be randomly assigned to one of two groups. One group will receive ERAS-based nutrition education along with a standardized fasting protocol to follow during the 24 hours before their surgery. The other group will receive routine preoperative care without the ERAS protocol. These treatments are behavioral and focus on education and fasting management according to evidence-based guidelines designed to reduce prolonged fasting and improve comfort. During the study, participants will be monitored for postoperative hydration levels, nausea and vomiting severity, and fluid intake and output balance within the first 48 hours after surgery. Validated tools like the Surgical Thirst Discomfort Scale and Rhodes Index of Nausea, Vomiting, and Retching will be used. Data on these outcomes will help understand the impact of the ERAS protocol on recovery and inform nursing care improvements. The study will involve preoperative education, surgery, and at least 48 hours of postoperative follow-up.

CONDITIONS

Brief Title

ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years and older
  • Scheduled for elective total knee arthroplasty
  • Expected hospital stay of at least 48 hours after surgery
  • Able to communicate verbally and provide informed consent
  • Adequate cognitive and neurological ability to understand study procedures
Not Eligible

You will not qualify if you...

  • Chronic diseases requiring fluid restriction
  • Cognitive impairment or psychiatric disorders affecting understanding (e.g., Alzheimer's, dementia, psychotic disorders)
  • Acute dehydration conditions before surgery (e.g., vomiting, diarrhea, excessive fluid loss)
  • Intraoperative complications needing intensive care
  • Postoperative follow-up less than 48 hours due to early discharge or transfer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) to assess eligibility and obtain informed consent

Preoperative Nutrition Education and Fasting Protocol

Duration - 24 hours prior to surgery

Participants receive ERAS-based preoperative nutrition education and follow an evidence-based fasting protocol during the 24 hours before total knee arthroplasty.

1 preoperative education session

Surgery

Duration - Day of surgery

Participants undergo elective total knee arthroplasty as planned.

1 visit (in-person) on the day of surgery

Postoperative Follow-up

Duration - 48 hours post-surgery

Participants are monitored for hydration status, nausea, vomiting, and fluid balance during the first 48 hours after surgery.

Approximately 2 days of in-hospital monitoring

Trial Site Locations

Total: 1 location

1

Acıbadem Health Group Atakent Hospital

Istanbul, Istanbul, Turkey (Türkiye), 34752

Actively Recruiting

Loading map...

Research Team

N

Nermin Ocaktan, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

A Comparison Between Palonosetron Versus Granisetron As Post...

Postoperative Nausea and Vomiting

Actively Recruiting

2 locations

Analgesic Efficacy of Different Liposomal Bupivacaine Doses ...

Pain, Postoperative

Actively Recruiting

1 location

Analgesic Efficacy of Preemptive Stepwise Infiltration Anest...

Total Knee Arthroplasty

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here