Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis.
J Derks, D Schaller, J Håkansson...
https://pubmed.ncbi.nlm.nih.gov/26701919Actively Recruiting
Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
ID06455306
Erythritol Air Polishing in Mucositis Treatment: A Randomized Controlled Trial
Led by University of Coimbra · Updated on 2024-06-12
24
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of air polishing systems compared to only oral hygiene instruction for treating peri-implant mucositis in adults aged 18 to 80 with at least one dental implant affected by this condition. This randomized clinical trial aims to understand if adding air polishing with erythritol powder improves treatment outcomes for this common inflammatory condition around dental implants. Participants are randomly assigned to one of three groups: one receiving a single air polishing treatment with erythritol plus oral hygiene instructions, another receiving monthly air polishing treatments with erythritol for three months plus oral hygiene instructions, and a control group receiving oral hygiene instructions alone. Treatments are provided by experienced periodontists, and clinical and biochemical assessments are conducted at baseline, 3 months, and 6 months. During the study, participants attend scheduled appointments for clinical examinations, X-rays, and collection of peri-implant crevicular fluid to analyze inflammation markers. Researchers will measure bleeding on probing, pocket depth, plaque levels, gingival recession, bone levels, and other outcomes to compare changes over time among groups. The total study duration includes follow-ups at 3 and 6 months after initial treatment to assess treatment effects and disease resolution.
CONDITIONS
Brief Title
Erythritol Air Polishing in Mucositis Treatment
Who Can Participate
Age: 18Years - 80Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 80 years
- At least one dental implant in function for a minimum of one year
- Diagnosed with peri-implant mucositis affecting at least one implant
You will not qualify if you...
- Pregnant or lactating women
- Unable to understand the treatment protocol or unable to sign informed consent
- Medical conditions preventing oral examination
- Unable to perform oral hygiene due to physical or mental disorders
- Uncontrolled systemic diseases, neoplasms, HIV or hepatitis infection, cardiovascular disease, blood disorders, or severe osteoporosis
- Use of systemic antibiotics, corticosteroids, or immunosuppressive therapy within 3 months before baseline
- Chronic use of nonsteroidal anti-inflammatory drugs or medications affecting periodontal health (e.g., phenytoin, cyclosporine)
- Alcohol or drug addiction
- Implants with mobility or occlusal overloads present in the affected site(s)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Treatment
Duration - Up to 3 months
Participants receive oral hygiene instructions and may receive air-polishing treatment with erythritol either once or monthly depending on their group assignment.
1 to 3 treatment visits depending on group assignment (in-person)
Follow-up
Duration - Up to 6 months
Participants attend follow-up visits for clinical examinations, radiographic assessments, and peri-implant crevicular fluid collection to monitor treatment outcomes.
Visits at 3 months and 6 months after baseline (in-person)
Trial Site Locations
Total: 1 location
1
University of Coimbra
Coimbra, Portugal
Actively Recruiting
Loading map...
Research Team
O
Orlando Martins
D
Diogo Banaco
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Peri-implant health, peri-implant mucositis, and peri-implantitis: Case definitions and diagnostic considerations.
Stefan Renvert, G Rutger Persson, Flavia Q Pirih...
https://pubmed.ncbi.nlm.nih.gov/29926496Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
Tord Berglundh, Gary Armitage, Mauricio G Araujo...
https://pubmed.ncbi.nlm.nih.gov/29926491Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis.
Chun-Teh Lee, Yen-Wen Huang, Liang Zhu...
https://pubmed.ncbi.nlm.nih.gov/28478213Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline.
David Herrera, Tord Berglundh, Frank Schwarz...
https://pubmed.ncbi.nlm.nih.gov/37271498Prevalence and risk/protective indicators of peri-implant diseases: A university-representative cross-sectional study.
Mario Romandini, Cristina Lima, Ignacio Pedrinaci...
https://pubmed.ncbi.nlm.nih.gov/33210772Non-surgical therapy of peri-implant mucositis-Mechanical/physical approaches: A systematic review.
Anders Verket, Odd Carsten Koldsland, Dagmar Bunaes...
https://pubmed.ncbi.nlm.nih.gov/36802083