Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04557995

Erythrocytapheresis for Chronic Mountain Sickness

Led by Third Military Medical University · Updated on 2026-04-02

112

Participants Needed

1

Research Sites

219 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to explore the efficacy and safety of erythrocytapheresis in chronic mountain sickness

CONDITIONS

Official Title

Erythrocytapheresis for Chronic Mountain Sickness

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Continuous residence at 2500 meters above sea level or higher for at least 1 year with no travel to low-altitude areas in the past 3 months
  • Hemoglobin level of at least 210 g/L for men or 190 g/L for women
  • Presence of at least one symptom or sign such as headache, dizziness, dyspnea, palpitations, sleep disturbances, fatigue, localized cyanosis, burning sensation in palms/soles, venous dilatation, muscle/joint pain, loss of appetite, poor concentration, or memory changes
  • Chronic Mountain Sickness total score of 6 or higher
  • Written informed consent provided by the patient or their legal representative
Not Eligible

You will not qualify if you...

  • Hematocrit less than 60%
  • Erythrocytosis caused by polycythemia vera, dehydration, cyanotic congenital heart disease, chronic obstructive pulmonary disease, or other blood or cancer-related conditions
  • Active pneumonia, pulmonary embolism, or severe organ dysfunction including heart, liver, or kidney failure
  • Contraindications to study procedures such as impaired consciousness, pneumothorax, severe arrhythmia, or significant coagulation disorders
  • Receipt of CMS-specific treatments like phlebotomy, erythrocytapheresis, or targeted drugs within the last 6 months
  • Pregnancy, breastfeeding, or planning pregnancy within 1 year
  • Terminal illness with life expectancy less than 6 months
  • Current participation in other clinical trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

NO.953 Hospital

Xigazê, Tibet, China, 857000

Actively Recruiting

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Research Team

J

Jieru Guo

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Erythrocytapheresis for Chronic Mountain Sickness | DecenTrialz