Actively Recruiting
Erythrocyte Transport of Lactate During Exercise (TELE Project)
Led by Technical University of Madrid · Updated on 2025-09-12
84
Participants Needed
2
Research Sites
390 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goals of this clinical trial are: 1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of the SLC16A1 gene (rs1049434), and the amount of MCT1 in erythrocytes membrane; 2. to analyze the levels of MCT1 in the erythrocytes membrane according to training status and genotype for the T1470A polymorphism of SLC16A1 (rs1049434). For this, the project will have two phases: * In phase I, trained participants will perform one maximal incremental test and one intervallic submaximal test with a final active recovery. * Phase II, levels of the MCT1 protein in the erythrocyte membrane will be quantified from trained and sedentary participants.
CONDITIONS
Official Title
Erythrocyte Transport of Lactate During Exercise (TELE Project)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- BMI between 18 and 25 kg/m2
- Not smoker
- In the case of trained participants: training at least 5 hours/week, of which at least 3 must be aerobic/anaerobic endurance training. Presentation of a medical certificate attesting to their medical fitness (capability) to perform intense physical exercise.
- In the case of sedentary participants, less than 1 day of training per week or less than 2 hours of structured exercise per week.
You will not qualify if you...
- Presenting any pathology that could impede the correct performance of the tests, or could influence the main study variables.
- In the case of the female sample, having irregular menstrual cycles, oligomenorrhea or amenorrhea.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Laboratorio de Pediatría. School of Medicine. Univesidad de Cantabria
Santander, Cantabria, Spain, 39011
Actively Recruiting
2
Laboratorio de Fisiología del Esfuerzo. Facultad de Ciencias de la Actividad Física y del Deporte (INEF). Universidad Politécnica de Madrid
Madrid, Madrid, Spain, 28040
Actively Recruiting
Research Team
R
Rocío Cupeiro, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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