Actively Recruiting

Age: 50Years +
All Genders
NCT07313462

Escalation vs. Induction Therapy Strategy in Patients With Early-Onset MS After Age 50

Led by University Hospital, Strasbourg, France · Updated on 2026-01-02

830

Participants Needed

1

Research Sites

51 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to evaluate the risk of inflammatory disease activity by retrospectively comparing two therapeutic strategies (escalation group and induction group). The investigators also aim to identify factors associated with inflammatory relapse and treatment-related complications.

CONDITIONS

Official Title

Escalation vs. Induction Therapy Strategy in Patients With Early-Onset MS After Age 50

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with relapsing-remitting multiple sclerosis (RRMS) onset after age 50
  • Patients who started their first disease-modifying therapy within 2 years of the first symptoms
  • Patients treated with moderately effective disease-modifying antirheumatic drugs (DMARDs) such as teriflunomide, dimethyl fumarate or diroximel fumarate, glatiramer acetate, interferon beta, or peginterferon
  • Patients treated with highly effective DMARDs such as fingolimod, ponesimod, natalizumab, rituximab, ocrelizumab, ofatumumab, or cladribine
Not Eligible

You will not qualify if you...

  • Patients with early progressive multiple sclerosis (MS)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre d'Investigation Clinique - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

N

Nicolas Collongues, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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