Actively Recruiting
Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia
Led by Beijing Tiantan Hospital · Updated on 2025-04-27
174
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
Sponsors
B
Beijing Tiantan Hospital
Lead Sponsor
B
Beijing Xiaotangshan Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
To assess the 1-month effects and safety of esketamine combined PRF and standardized treatment to relieve pain in patients with acute/subacute zoster-related trigeminal neuralgia(ZRTN).
CONDITIONS
Official Title
Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- History of herpes zoster within the last three months
- Lesions located in regions served by the trigeminal nerve or its branches
- Numeric Rating Scale pain score of 4 or higher despite medication
- Planned CT-guided pulsed radiofrequency treatment of the Gasserian ganglion
You will not qualify if you...
- Obstructive sleep apnea syndrome
- Receiving other invasive treatments like spinal cord stimulation
- History of systemic immune diseases, organ transplantation, or cancers
- Severe heart, lung, liver, or kidney dysfunction
- History of schizophrenia, epilepsy, myasthenia gravis, or delirium
- Hyperthyroidism or phaeochromocytoma
- Recent drug abuse
- Contraindications to esketamine
- Communication difficulties
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital
Beijing, China, 100050
Actively Recruiting
Research Team
F
Fang Luo, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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