Actively Recruiting

Phase Not Applicable
Age: 20Years - 65Years
All Genders
NCT06108830

Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients

Led by Tianjin Medical University General Hospital · Updated on 2024-09-04

400

Participants Needed

1

Research Sites

53 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To explore the effects of esketamine combined with remimazolam on postoperative sleep disturbance and anxiety in surgical patients undergoing gastroenteroscopies

CONDITIONS

Official Title

Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients

Who Can Participate

Age: 20Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 20-65 years old
  • ASA classification grade I to III
  • Scheduled for elective surgery
  • Body mass index between 19 and 30 kg/m2
  • Voluntary agreement to participate in the study
Not Eligible

You will not qualify if you...

  • Allergy to any drug ingredients used in the study or allergic constitution
  • History of allergy to general anesthesia drugs, opioid drugs, or non-steroidal drugs
  • History of neurological diseases or chronic pain
  • Drug or alcohol addiction, long-term opioid use, or opioid use within 48 hours before surgery
  • ASA classification grade IV or V
  • Coronary heart disease, bronchial asthma, severe hypertension, severe blood disorders, liver or kidney dysfunction, or electrolyte imbalances
  • History of gastrointestinal diseases such as peptic ulcer, Crohn's disease, or ulcerative colitis
  • Respiratory insufficiency or respiratory failure
  • Refusal to use intravenous patient-controlled analgesia (PCA)
  • Pregnant or breastfeeding women
  • Body mass index less than 18 kg/m2 or greater than 30 kg/m2
  • Poor compliance or inability to complete the study procedures
  • Participation in other clinical drug trials within the last 4 weeks
  • Any condition the researcher considers unsuitable for participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tianjin Medical University General Hospital

Tianjin, China, 300052

Actively Recruiting

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Research Team

G

Guolin Wang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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