Comparing Esmolol and Sufentanil for Recovery Quality After Outpatient Laparoscopic Gallbladder Surgery Under General Anaesthesia with Orotracheal Intubation

What this Trial Is About

Researchers are evaluating the use of Esmolol compared to Sufentanil during general anesthesia for outpatient laparoscopic cholecystectomy with orotracheal intubation. The study aims to see if Esmolol can provide an equivalent quality of recovery and pain control after surgery, potentially avoiding some side effects linked to morphine-based drugs like Sufentanil. Esmolol is a cardioselective beta-blocker that acts quickly and may offer benefits in outpatient settings. The study involves 120 adult patients scheduled for outpatient laparoscopic cholecystectomy. Participants are randomly assigned to receive either Esmolol 1 to 1.5 mgkg at induction or Sufentanil 0.1 to 0.3 mcgkg at induction during anesthesia. The trial includes three visits an inclusion visit for eligibility screening and consent, a surgery day visit with randomization and monitoring, and a follow-up telephone visit the day after surgery to assess recovery and painkiller use. During the study, researchers will collect data on vital signs, patient characteristics, and recovery quality using a 15-question questionnaire conducted over the phone after surgery. They will monitor patient comfort and pain control, as well as medication use at home. Participants vital signs and eligibility are carefully checked before surgery, and the study lasts about two days per participant with ongoing medical supervision and the option to withdraw at any time.

Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intubation on an Outpatient Basis