Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04214119

EsophaCap for the Detection of Early Esophageal Carcinoma

Led by Johns Hopkins University · Updated on 2025-12-16

2500

Participants Needed

2

Research Sites

675 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.

CONDITIONS

Official Title

EsophaCap for the Detection of Early Esophageal Carcinoma

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Undergoing esophagogastroduodenoscopy at Johns Hopkins Hospital from 1/2016 to 12/2025
  • Age greater than 18 years
  • Patients must be able to swallow a capsule
Not Eligible

You will not qualify if you...

  • Patients with extra-esophageal malignancies including head and neck and gastric cancer
  • Patients who have undergone esophagectomy
  • Patients who have undergone radiation to the chest
  • Patients younger than 18 years
  • Patients with esophageal stents
  • Patients with esophageal strictures preventing passage of the capsule

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Bayview Medical Center

Baltimore, Maryland, United States, 21205

Actively Recruiting

2

Johns Hopkins Hospital

Baltimore, Maryland, United States, 21205

Actively Recruiting

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Research Team

S

Stephen J Meltzer, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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EsophaCap for the Detection of Early Esophageal Carcinoma | DecenTrialz