Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05271331

ESP Block Versus Wound Infiltration for Laminectomy

Led by University of Padova · Updated on 2025-06-26

112

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Spinal surgery is often burdened by perioperative pain and its treatment presently represents a challenge for anesthetists. An inadequate intra and postoperative analgesic therapy leads to a delay in the mobilization of the patients, prolonged hospital stay and thromboembolic complications, as well as the onset of chronic pain syndromes . Effective pain treatment can help improve surgical outcome for patients undergoing spinal surgery. From the pathophysiological point of view pain in vertebral surgery can originate from different anatomical structures: vertebrae, discs, ligaments, dura mater, facet joints, muscles and skin-subcutis. The terminal innervation of these tissues originate from the dorsal branches of the spinal nerves, and this represents a target a multimodal approach to perioperative analgesia in vertebral surgery. Systemically administered drugs such as NSAIDs, opioids, ketamine, intravenous lidocaine could benefit from the addition of locoregional therapies such as neuraxial blocks (anesthesia peridural or subarachnoid) or as shown more recently by other anesthesia techniques locoregional ultrasound-guided In recent years the anesthesiological interest has focused on the Erector Spinae Plane Block (ESPB). First described by Forero et al, it is a paraspinal interfascial block targeting the dorsal and ventral branches of the spinal nerves just after their emergence from the spinal cord. In the ultrasound-guided technique the local anesthetic is injected between the deep fascia of the muscle itself and the transverse processes of the vertebrae at the level interested. The aim of this study is to evaluate the efficacy of ESPB when compared to wound infiltration in patients undergoing laminectomy

CONDITIONS

Official Title

ESP Block Versus Wound Infiltration for Laminectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Planned 1 or 2 level surgical laminectomy
Not Eligible

You will not qualify if you...

  • Allergy to local anesthetics
  • Refusal of consent
  • Uncompensated heart disease, kidney disease, liver disease, or peripheral neuropathies
  • Blood disorders that increase bleeding risk
  • Gastrointestinal ulcer or bleeding
  • Local infection at the site
  • Psychiatric or neurological disorders (except those related to the primary disease for surgery)
  • History of substance abuse or use within 24 hours before surgery
  • Alcohol addiction
  • American Society of Anesthesiologists (ASA) physical status greater than 3

AI-Screening

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Trial Site Locations

Total: 1 location

1

University Hospital of Padova

Padova, Veneto, Italy, 35127

Actively Recruiting

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Research Team

A

Alessandro De Cassai

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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ESP Block Versus Wound Infiltration for Laminectomy | DecenTrialz