Regional analgesia for acute pain relief after open thoracotomy and video-assisted thoracoscopic surgery.
S Mehta, T T H Jen, D L Hamilton
https://pubmed.ncbi.nlm.nih.gov/37465231Actively Recruiting
Led by Bursa City Hospital · Updated on 2025-12-16
90
Participants Needed
1
Research Sites
N/A
Total Duration
B
Bursa City Hospital
Lead Sponsor
U
Ulusoy, Emre, M.D.
Collaborating Sponsor
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive procedure using small chest incisions, but patients often experience significant postoperative pain due to tissue and rib trauma. Poorly controlled pain can lead to chronic issues, so effective pain relief is crucial. This study compares two types of nerve blocks, erector spinae plane block (ESPB) and the newer serratus posterior superior intercostal plane block (SPSIPB), to evaluate their effectiveness and patient satisfaction in managing pain after VATS. Participants will receive either the ESPB or SPSIPB nerve block during surgery. Both involve using ultrasound guidance to inject a local anesthetic containing bupivacaine and epinephrine near specific muscles and nerves in the back or upper chest area. The SPSIPB targets nerves between the C3 and T10 spinal levels, while the ESPB targets the T5 level. This comparison aims to determine which block provides better pain control after VATS. During the study, opioid use will be measured at multiple times within the first 24 hours after surgery to assess pain control. Pain scores will be recorded using a numerical scale, and patient recovery quality will be evaluated 24 hours post-surgery. Additional assessments include pain inventories and anxiety/depression scales at three months after surgery. Participants will be monitored closely throughout the study period, which runs until May 2026.
CONDITIONS
ESP vs SPSIP Block in VATS Analgesia
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 24 hours post-surgery
Participants undergo video-assisted thoracoscopic surgery (VATS) and receive either an erector spinae plane block (ESPB) or serratus posterior superior intercostal plane block (SPSIPB) for postoperative pain relief.
1 surgical visit and assessments at 0, 2, 4, 8, 16, and 24 hours post-surgery
Duration - 3 months
Participants are assessed for pain, recovery, and psychological status after surgery, including evaluations at 3 months postoperatively.
1 follow-up visit at 3 months post-surgery
Total: 1 location
1
Bursa City Hospital
Bursa, Nilüfer, Turkey (Türkiye), 16110
Actively Recruiting
E
Eralp Çevikkalp
E
Emre ULUSOY
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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S Mehta, T T H Jen, D L Hamilton
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