Actively Recruiting
ESPB vs SPSIP for Postoperative Analgesia After CABG
Led by Kutahya Health Sciences University · Updated on 2026-05-13
64
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in adult patients (45-85 years, ASA I-III) undergoing elective coronary artery bypass graft surgery. The primary outcome is postoperative pain intensity assessed by Numeric Rating Scale (NRS) at 2, 4, 8, 16, 24, and 48 hours after surgery. Secondary outcomes include intraoperative fentanyl/remifentanil consumption, postoperative morphine consumption, patient-controlled analgesia (PCA) demand/delivery parameters (if PCA is used), need for rescue analgesics, extubation and mobilization times, peak inspiratory flow measured by incentive spirometry at predefined time points, ICU and hospital length of stay, recovery quality (QoR-15 at 0, 24, and 48 hours), mortality, and block-related adverse events.
CONDITIONS
Official Title
ESPB vs SPSIP for Postoperative Analgesia After CABG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 45 to 85 years
- Scheduled for elective coronary artery bypass graft surgery
- American Society of Anesthesiologists (ASA) physical status I, II, or III
- Provide written informed consent and agree to participate in the study
You will not qualify if you...
- Emergency cases
- ASA physical status IV or V
- Known allergy to local anesthetics
- Blood clotting problems (platelet count <100,000/mm³, INR >1.5, aPTT >1.5 times normal)
- Infection at the injection site for the nerve block
- Pregnancy
- Do not provide written informed consent or decline to participate after being informed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kütahya Health Sciences University Hospital
Kütahya, Kütahya, Turkey (Türkiye), 43100
Actively Recruiting
Research Team
M
Merve Yaman, Assistant Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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