Comparing Two Ultrasound-Guided Nerve Block Techniques for Pain Relief After Coronary Artery Bypass Surgery in Adults Aged 45 to 85

What this Trial Is About

Researchers are comparing two types of ultrasound-guided nerve blocks to manage pain after coronary artery bypass graft CABG surgery in adults aged 45 to 85 years with ASA physical status I to III. The study evaluates the effectiveness and safety of the Erector Spinae Plane Block ESPB versus the Serratus Posterior Superior Intercostal Plane Block SPSIPB in controlling postoperative pain. This randomized, double-blind trial aims to better understand pain relief options following heart surgery. Participants will receive one of two nerve block procedures before surgery under sedation. The ESPB involves injecting 20 mL of 0.25% bupivacaine on each side at the T4-T5 vertebral level, while the SPSIPB involves the same dose at the 2nd-3rd intercostal space. All participants will undergo standardized general anesthesia for their CABG surgery and receive the same postoperative multimodal pain management plan. Throughout the study, participants pain intensity will be measured at multiple times up to 48 hours after surgery using a numeric rating scale. Researchers will also track opioid use, need for additional pain relief, recovery quality, lung function, time to extubation and mobilization, length of ICU and hospital stay, and any block-related side effects. The study will be conducted from March to September 2026, with careful monitoring to assess safety and pain control outcomes.

ESPB vs SPSIP for Postoperative Analgesia After CABG