Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
FEMALE
NCT06091241

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Led by University of Kansas Medical Center · Updated on 2025-07-09

102

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants. Deep Inferior Epigastric Perforator (DIEP) flaps are the gold standard for autologous breast reconstruction . Effective pain control following surgery is imperative and ultrasound-guided bilateral transversus abdominis plane blocks (TAPs) with the infiltration of local anesthetics, such a bupivacaine are a common regional technique of choice . A newer described technique, bilateral Erector Spinae Plane blocks (ESPBs) (which also are an infiltration of local anesthetic) present as an alternative approach for post-operative analgesia. ESPBs have been proven efficacious in reducing intra- and post-operative opioid requirements, lessening the need for rescue analgesics in other similar surgical procedures. The hypothesis is that preoperative bilateral ESPBs could provide equivalent pain control as a regional analgesic for patients undergoing DIEP flap surgery when compared to preoperative bilateral TAPs

CONDITIONS

Official Title

ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery

Who Can Participate

Age: 18Years - 70Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult women with breast cancer
  • ASA physical status classification 1 to 3
  • Scheduled for DIEP flap surgery
Not Eligible

You will not qualify if you...

  • Chronic opioid use
  • Contraindications to local anesthetics or regional analgesia
  • Inability to communicate pain intensity using a numeric scale

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Kansas Medical Center

Kansas City, Kansas, United States, 66160

Actively Recruiting

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Research Team

R

Rachel Henning

CONTACT

M

Manuel Clark

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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