Actively Recruiting
Establish and Characterize an Acute HIV Infection Cohort in a High Risk Population
Led by SEARCH Research Foundation · Updated on 2026-04-27
777
Participants Needed
1
Research Sites
1265 weeks
Total Duration
On this page
Sponsors
S
SEARCH Research Foundation
Lead Sponsor
A
Armed Forces Research Institute of Medical Sciences, Thailand
Collaborating Sponsor
AI-Summary
What this Trial Is About
To describe clinical, immunological, and virological characteristics of persons with acute HIV infection 1. To describe demographics and behavioral risk factors for those identified with acute HIV infection 2. To describe neurocognitive function and neuroimaging findings in acute HIV infection as well as describe immune response, HIV-1 genotypes and sequences in the cerebrospinal fluid. 3. To describe the number and characteristics of sexual contacts 4. To describe the willingness of acute HIV-infected subjects to allow the tracking of their sexual contacts for voluntary HIV counseling and testing (VCT) 5. To describe immune response, HIV-1 genotypes and sequences in the genital compartment 6. To describe T cell depletion in the gut mucosa in acute HIV infection and describe the changes in gut T cell during follow up 7. To archive samples for future investigations including determination of viral evolution, and cell-mediated and humoral immune responses in peripheral blood and mucosal compartments
CONDITIONS
Official Title
Establish and Characterize an Acute HIV Infection Cohort in a High Risk Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years old
- Have protocol-defined acute HIV-1 infection confirmed by specific blood tests
- Understand the study and sign the informed consent form (or provide thumb print if unable to read)
- Be available for follow-up for the planned study duration
You will not qualify if you...
- History of medical or psychiatric disorder that interferes with study adherence or informed consent
- Female participants who are pregnant at the time of screening
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institute of HIV Research and Innovation (IHRI)
Bangkok, Bangkok, Thailand, 10330
Actively Recruiting
Research Team
N
Nittaya Phanuphak, MD, PhD
CONTACT
N
Nitiya Chomchey
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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