Follow-up Study of Migraine Patients With Patent Foramen Ovale to Explore Treatment and Prognosis

What this Trial Is About

Researchers are establishing a headache center in China to study migraine patients who also have patent foramen ovale PFO. The study aims to explore different treatment options for this combination, identify factors that may influence outcomes, and develop models to predict prognosis. The goal is to improve understanding and care for patients with both conditions. Participants will be assigned to one of three groups based on treatment approach a conservative group that does not use antiplatelet drugs or undergo PFO closure surgery, a group that receives antiplatelet drug treatment, and a group that undergoes PFO closure surgery. The study is observational and will follow patients over time to monitor their condition. During the study, participants will be regularly monitored for changes in migraine attacks at 3 months, 6 months, 1 year, 2 years, and 3 years. The study involves clinical, imaging, and laboratory examinations to gather detailed information. Participants will be followed up to assess the effects of their treatment approach and factors influencing migraine outcomes with PFO.

Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale