Actively Recruiting

All Genders
NCT05791786

The Establishment of a Registry and a Biorepository of Patients With Suspected Amniotic Fluid Embolism (AFE)

Led by The University of Texas Health Science Center, Houston · Updated on 2026-05-08

400

Participants Needed

1

Research Sites

495 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center, Houston

Lead Sponsor

A

Amniotic Fluid Embolism (AFE) Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

To establish a clinical registry of suspected cases of AFE. The existing registry will be migrated to a new platform,

CONDITIONS

Official Title

The Establishment of a Registry and a Biorepository of Patients With Suspected Amniotic Fluid Embolism (AFE)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Amniotic Fluid Embolism (AFE) or suspected AFE
  • Ability of participant or next of kin to provide a signed and dated informed consent form
  • Surviving family members or next of kin of lethal AFE cases able to provide consent, death certificate, and proof of kinship
  • Willingness to permit collection of data about affected pregnancy, previous and future pregnancies, and health conditions
  • Inclusion of any maternal death at Hermann Hospital System suspected of AFE within 24 hours of childbirth from 1/2012 to 1/2023
  • Medical records reviewed by experts to classify cases as classic AFE, atypical AFE, not AFE, or indeterminate
Not Eligible

You will not qualify if you...

  • Inability or unwillingness to provide a signed and dated informed consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

M

Miranda Klassen

CONTACT

I

Irene Stafford, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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