Establishment and Validation of a Clinical Predictive Model for Gastrointestinal Cancer Screening Based on Patient-related Risk Factors: a Prospective, Multicenter Cross-sectional Study

What this Trial Is About

Gastrointestinal tumors, including esophageal, gastric, and colorectal cancers, pose a serious health threat due to their high incidence and cancer-related mortality. Early detection through digestive endoscopy can significantly improve prognosis, with early-stage tumors having a five-year survival rate of up to 90%, compared to less than 30% for late-stage tumors. This research aims to identify the combined risk factors for these cancers and establish a predictive model for screening based on patient-related factors such as age, gender, family history, smoking, and alcohol use. This prospective, multicenter, cross-sectional observational study enrolls adults aged 18 to 80 who are undergoing both gastroscopy and colonoscopy. The study does not involve experimental treatments but focuses on collecting patient data to understand the overall risk factors associated with gastrointestinal tumors and develop a comprehensive risk prediction model. Participants will be assessed during their screening procedures, with data collected on their risk factors and health status. The primary outcome measured is the overall detection rate of gastrointestinal cancer over a two-year period. Researchers will analyze this data to improve early screening strategies. Participation involves no treatment intervention, but thorough information gathering during endoscopic examinations and follow-up over time.

Establishment and Validation of a Clinical Predictive Model for Gastrointestinal Cancer Screening Based on Patient-related Risk Factors