Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
FEMALE
Healthy Volunteers
NCT05962775

Ethanol Sclerotherapy Prior to ART

Led by Ankara University · Updated on 2024-10-16

84

Participants Needed

3

Research Sites

152 weeks

Total Duration

On this page

Sponsors

A

Ankara University

Lead Sponsor

H

Hacettepe University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1. Does ethanol sclerotherapy before ART cycle has any impact on cumulative live birth rate in patients with endometrioma? 2. Does ethanol sclerotherapy improve chronic pelvic pain, dysmenorrhea, complications during oocyte retrieval, response to ovarian stimulation (number of mature oocytes retrieved), and pregnancy loss rates? Infertile patients with endometrioma between 4-10 cm who are scheduled for ART within 2 cycles will be randomized to ethanol sclerotherapy or no intervention.

CONDITIONS

Official Title

Ethanol Sclerotherapy Prior to ART

Who Can Participate

Age: 18Years - 40Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients aged 18 to 40 years
  • Anti-mullerian hormone (AMH) level greater than 0.3 ng/ml
  • Presence of unilateral or bilateral endometrioma
  • Endometrioma cyst diameter between 40 and 100 mm
Not Eligible

You will not qualify if you...

  • History of three or more failed IVF or embryo transfer attempts
  • Menstrual cycle abnormalities
  • Male factor infertility
  • Presence of uterine fibroids
  • Presence of hydrosalpinx
  • Presence of uterine abnormalities
  • Suspicion of malignancy based on International Ovarian Tumor Analysis criteria

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Başkent University Adana IVF Center

Adana, Turkey (Türkiye)

Actively Recruiting

2

Ankara University School of Medicine, Department of Obstetrics and Gynecology

Ankara, Turkey (Türkiye), 06610

Actively Recruiting

3

Bahçeci IVF Clinic

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

Y

Yavuz Emre Sukur

CONTACT

S

Sezcan Mumusoglu

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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