Actively Recruiting
Ethnic Specificities of S100B Protein Blood Level in Guadeloupe: Cross-sectional Study in Healthy Subjects
Led by Centre Hospitalier Universitaire de la Guadeloupe · Updated on 2025-05-31
200
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how the S100B protein blood levels vary among individuals with different ethnic backgrounds, particularly in Guadeloupe where the majority have a Black phenotype. This study aims to confirm if physiological levels of S100B protein differ by skin phenotype, which is important because current thresholds for using S100B to reduce CT scans in minor traumatic brain injury may not accurately apply to this population. Prior studies suggest higher S100B levels in Black individuals, but data is limited and variable. The study will involve hospital staff from the University Hospital of Guadeloupe and the Hospital of Basse-Terre who meet eligibility criteria. Participants will provide informed consent, complete an anonymous questionnaire about their ethnicity, age, sex, and weight, and provide a blood sample. This sample will be analyzed at the hospital laboratory to measure the S100B protein level and assess its correlation with ethnicity and skin phototype. Participants will be involved in completing questionnaires and blood collection during the study. Researchers will measure baseline S100B protein levels and analyze these in relation to ethnicity and skin phototype. The study is observational, and no treatments or interventions are administered. The information gathered will help improve the use of S100B testing in clinical practice for populations with diverse ethnic backgrounds, over the course of the study period ending in August 2025.
CONDITIONS
Brief Title
Ethnic Specificities of S100B Protein Blood Level in Guadeloupe: Cross-sectional Study in Healthy Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospital staff of the University Hospital of Guadeloupe or the Hospital of Basse-Terre
- Age between 18 and 65 years
- Individuals willing to specify their ethnic origin and skin phototype
- Individuals affiliated with or beneficiaries of a social security scheme
- Informed individuals who have given their voluntary, informed, and written consent
You will not qualify if you...
- Individuals on anticoagulant therapy
- Individuals with a personal history of neurological disease
- Individuals with a personal history of melanoma
- Refusal to participate
- Individuals under guardianship, curatorship, or legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants complete a questionnaire and provide a blood sample for S100B protein analysis to assess ethnic-specific protein levels.
1 visit (in-person)
Trial Site Locations
Total: 2 locations
1
CH de la Basse-Terre
Basse-Terre, Guadeloupe, 97109
Actively Recruiting
2
Chu de La Guadeloupe
Pointe-à-Pitre, Guadeloupe, 97159
Actively Recruiting
Research Team
V
Valérie Hamony Soter
M
Mélanie Petapermal
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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