Actively Recruiting

Age: 30Years - 85Years
All Genders
NCT07386015

Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

Led by Tianjin Huanhu Hospital · Updated on 2026-03-10

700

Participants Needed

1

Research Sites

248 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a prospective, multicenter, observational cohort (patient registry) designed to better understand freezing of gait (FOG), a disabling walking problem that can occur in Parkinson's disease and other related neurological conditions.The purpose of this registry is to collect long-term clinical information from patients with freezing of gait or gait and balance problems, and to explore how different causes of FOG are related to symptoms, walking patterns, falls, disease progression, and outcomes over time. The study will include participants with Parkinson's disease and other conditions associated with freezing of gait.Participants will receive standard medical care as determined by their treating physicians. No experimental drugs or study-related treatments will be assigned as part of this registry. Clinical information will be collected during routine visits and follow-up assessments, including questionnaires, walking and balance evaluations, video recordings, and other commonly used clinical tests.The information collected in this study may help improve the understanding of freezing of gait, support better risk assessment for falls, and guide future research and clinical management strategies for patients with gait and balance disorders.

CONDITIONS

Official Title

Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

Who Can Participate

Age: 30Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 30 and 85 years
  • Presence of freezing of gait or gait or balance impairment
  • Diagnosis of Parkinson's disease or related parkinsonian disorders including PD, PSP, MSA, DLB, CBD, vascular parkinsonism, or idiopathic normal pressure hydrocephalus
  • Ability to complete gait and balance assessment tasks independently or with assistance
  • Ability and willingness to provide written informed consent
Not Eligible

You will not qualify if you...

  • Severe dementia with Mini-Mental State Examination score less than 10
  • Severe psychiatric disorders that interfere with study participation
  • Severe cardiopulmonary, musculoskeletal, or other medical conditions significantly affecting gait safety
  • Stroke, fracture, or other major medical events within the past 3 months
  • Inability to comply with follow-up procedures
  • Refusal to allow video or speech data collection

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Tianjin Huanhu Hospital

Tianjin, Tianjin Municipality, China, 300350

Actively Recruiting

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Research Team

P

Peipei Liu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG) | DecenTrialz