Helicobacter pylori eradication as the sole treatment for gastric and duodenal ulcers.
Perttu Et Arkkila, Kari Seppälä, Timo U Kosunen...
https://pubmed.ncbi.nlm.nih.gov/15647648Actively Recruiting
Age: 18Years +
All Genders
ID02328131
European Registry on the Management of Helicobacter Pylori Infection
Led by Javier P. Gisbert · Updated on 2024-10-02
10000
Participants Needed
30
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Helicobacter pylori infection is a common chronic stomach infection linked to serious conditions like gastritis, peptic ulcers, and gastric cancer. This research aims to collect real-world data from European gastroenterologists on how H. pylori infection is diagnosed, treated, and managed over time. The goal is to analyze current clinical practices, evaluate treatment effectiveness and safety, and improve healthcare strategies across Europe. The study uses a non-interventionist, prospective registry design involving up to ten gastroenterologists from 30 European countries. These doctors will record their routine clinical care of H. pylori infected adult patients over ten years using an electronic case report form. Data collected includes patient demographics, diagnosis methods, treatment details, adherence, side effects, and treatment outcomes. Participants will be adults diagnosed with H. pylori infection seen in outpatient digestive clinics. Information on prescribed treatments and eradication confirmation will be gathered systematically. Researchers will monitor treatment prescriptions, adverse events, and treatment success rates during the study. The registry allows future analyses approved by the scientific committee, supporting better understanding and management of H. pylori infection.
CONDITIONS
Brief Title
European Registry on the Management of Helicobacter Pylori Infection
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Infected adult patients by Helicobacter pylori (18 years or older)
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Monitoring
Duration - Up to 1 year
Participants who undergo routine care for Helicobacter pylori infection are observed and their diagnostic, treatment, and outcome data are collected over time.
Visits as part of routine clinical practice over 1 year
Trial Site Locations
Total: 30 locations
1
Medical University Wien
Vienna, Austria
Actively Recruiting
2
CHU de Charleroi, Charleroi
Charleroi, Belgium
Actively Recruiting
3
Medical University of Sofia
Sofia, Bulgaria
Actively Recruiting
4
University Hospital Merkur
Zagreb, Croatia
Actively Recruiting
5
Charles University Faculty of Medicine
Prague, Czechia
Actively Recruiting
6
Køge University Hospital
Køge, Denmark
Actively Recruiting
7
University of Tartu
Tartu, Estonia
Actively Recruiting
8
Herttoniemi Hospital, Helsinki
Helsinki, Finland
Actively Recruiting
9
Hôpital Pellegrin
Bordeaux, France
Actively Recruiting
10
Medizin Uni Magdeburg
Magdeburg, Germany
Actively Recruiting
11
Gastroenterology Clinic, Henry Dunant Hospital
Athens, Greece
Actively Recruiting
12
Ferencváros Health Centre, Gaastroenterology
Budapest, Hungary
Actively Recruiting
13
Adelaide Meath Hospital, Dublin
Dublin, Ireland
Actively Recruiting
14
Studio Gasbarrini
Roma, Italy
Actively Recruiting
15
Digestive Diseases Centre GASTRO
Riga, Latvia
Actively Recruiting
16
Lithuanian university of Health Sciences Hospital
Kaunas, Lithuania
Actively Recruiting
17
Ikazia Ziekenhuis/ Erasmus Medisch Centrum
Rotterdam, Netherlands
Actively Recruiting
18
Central Hospital of Ostfold
Fredrikstad, Norway
Actively Recruiting
19
Departament of Gastroenterology, Medical Centre for Postgraduate Education
Warsaw, Poland
Actively Recruiting
20
Porto
Porto, Portugal
Actively Recruiting
21
Timisoara
Timișoara, Romania
Actively Recruiting
22
Central Scientific Research Institute of Gastroenterology
Moscow, Russia
Actively Recruiting
23
Clinical Center of Serbia
Belgrade, Serbia
Actively Recruiting
24
DC Rogaska
Rogaška Slatina, Slovenia
Actively Recruiting
25
Hospital de La Princesa, Madrid
Madrid, Spain
Actively Recruiting
26
Uppsala University Hospital.
Uppsala, Sweden
Actively Recruiting
27
University Hospital Basel
Basel, Switzerland
Actively Recruiting
28
Dokuz Eylul University School of Medicine
Izmir, Turkey (Türkiye)
Actively Recruiting
29
National Medical University
Kiev, Ukraine
Actively Recruiting
30
Leeds General Infirmiry Hospital
Leeds, United Kingdom
Actively Recruiting
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Research Team
J
Javier Pérez Gisbert, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
The epidemiology of Helicobacter pylori and public health implications.
Nuno F Azevedo, Janis Huntington, Karen J Goodman
https://pubmed.ncbi.nlm.nih.gov/19712161Risk factors for failure of Helicobacter pylori therapy--results of an individual data analysis of 2751 patients.
N Broutet, S Tchamgoué, E Pereira...
https://pubmed.ncbi.nlm.nih.gov/12492738Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands.
Annemarie C de Vries, Nicole C T van Grieken, Caspar W N Looman...
https://pubmed.ncbi.nlm.nih.gov/18395075How can the current strategies for Helicobacter pylori eradication therapy be improved?
Alex Ford, Paul Moayyedi
https://pubmed.ncbi.nlm.nih.gov/12845349Epidemiology of Helicobacter pylori infection and public health implications.
Alexander C Ford, Anthony T R Axon
https://pubmed.ncbi.nlm.nih.gov/21054646Review article: the effectiveness of standard triple therapy for Helicobacter pylori has not changed over the last decade, but it is not good enough.
J P Gisbert, X Calvet
https://pubmed.ncbi.nlm.nih.gov/22017749Sequential therapy for Helicobacter pylori eradication: a critical review.
Javier P Gisbert, Xavier Calvet, Anthony O'Connor...
https://pubmed.ncbi.nlm.nih.gov/20054285Review article: non-bismuth quadruple (concomitant) therapy for eradication of Helicobater pylori.
J P Gisbert, X Calvet
https://pubmed.ncbi.nlm.nih.gov/21745241H. pylori eradication therapy vs. antisecretory non-eradication therapy (with or without long-term maintenance antisecretory therapy) for the prevention of recurrent bleeding from peptic ulcer.
J P Gisbert, S Khorrami, F Carballo...
https://pubmed.ncbi.nlm.nih.gov/15106235