Actively Recruiting
EUS-guided RFA for Pancreatic Neoplasms
Led by Chinese University of Hong Kong · Updated on 2026-03-20
30
Participants Needed
1
Research Sites
560 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. Recently, EUS-guided RFA has become available and the device allows EUS-guided treatment of pancreatic neoplasms. The procedure has been shown to be feasible in the porcine pancreas and was used to treat small groups of patients that are not suitable for surgery suffering from pancreatic neoplasms. The aim of the current study is to perform a multi-center prospective study on EUS-guided radiofrequency ablation (RFA) of solid pancreatic neoplasms. The hypothesis is that EUS-guided RFA is safe, feasible and effective for treating solid pancreatic neoplasms.
CONDITIONS
Official Title
EUS-guided RFA for Pancreatic Neoplasms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years-old or above
- Diagnosed with pancreatic neuroendocrine tumor or pancreatic ductal carcinoma smaller than 5 cm confirmed by fine needle aspiration cytology
- Unsuitable for surgery due to ASA score greater than II, an advanced malignancy, or expert opinion
- Healthy individuals not interested in surgical resection
- Eligible for endoscopic intervention
- Provided written informed consent
You will not qualify if you...
- Coagulopathy (international normalized ratio greater than 1.3, partial thromboplastin time more than twice control), or platelet count below 50,000 x10^3/uL
- Pregnancy
- Poor mental condition or mental retardation preventing understanding of the study
- Unwilling to undergo follow-up assessments
- Presence of liver cirrhosis, portal hypertension, or gastric varices
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Surgery, Prince of Wales Hospital
Hong Kong, Hong Kong
Actively Recruiting
Research Team
A
Anthony YB Teoh, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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