Actively Recruiting
EUS-guided RFA for Solid Abdominal Neoplasms
Led by Chinese University of Hong Kong · Updated on 2026-03-20
30
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. Recently, EUS-guided RFA has become available and the device allows EUS-guided treatment of solid abdominal neoplasms. The procedure has been shown to be feasible in the porcine pancreas and was used to treat small groups of patients that are not suitable for surgery suffering from pancreatic cancers. The aim of the current study is to perform a multi-center prospective study on EUS-guided radiofrequency ablation (RFA) of solid abdominal neoplasms. The hypothesis is that EUS-guided RFA is safe, feasible and effective for treating solid abdominal neoplasms.
CONDITIONS
Official Title
EUS-guided RFA for Solid Abdominal Neoplasms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years-old or above
- Suffering from solid neoplasms of the stomach, liver, kidney or adrenals (<5cm in largest diameter) indicated for treatment
- Unsuitable for surgery due to one or more of the following: ASA score > II, an alternative advanced malignancy, or expert opinion for any other reason
- Healthy individuals who are not keen on surgical resection
- Eligible for endoscopic intervention
- Written informed consent
You will not qualify if you...
- Coagulopathy (INR >1.3, partial thromboplastin time greater than twice control), platelet count <50,000x10^3/uL
- Pregnancy
- Poor mental condition or mental retardation preventing understanding of the study
- Unwillingness to undergo follow-up assessments
- Liver cirrhosis, portal hypertension, and/or gastric varices
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Surgery, Prince of Wales Hospital
Hong Kong, Hong Kong
Actively Recruiting
Research Team
A
Anthony YB Teoh, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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