Actively Recruiting
EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)
Led by NYU Langone Health · Updated on 2025-11-28
15
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
Sponsors
N
NYU Langone Health
Lead Sponsor
T
Taewoong Medical
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a single arm study in the treatment of pancreatic ductal adenocarcinoma (PDAC). The investigators propose to test the tolerability of chemotherapy plus endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) using the RF Electrode in patients receiving palliative second or third line therapy for unresectable non-metastatic pancreatic cancer.
CONDITIONS
Official Title
EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed and histologically confirmed pancreatic ductal adenocarcinoma (PDAC) by biopsy
- Axial CT scan or MRI showing PDAC with at least 1 cm in greatest diameter
- ECOG performance status of 0 to 2
- Locally advanced PDAC with no response or progression after first line chemotherapy
- Tumor deemed unresectable after multidisciplinary review
- No evidence of distant metastasis
- Tumor lesions between 1 and 4 cm in size
You will not qualify if you...
- Evidence of distant metastasis
- Tumor mass not accessible by endoscopy
- Pregnancy
- Unable to provide informed consent
- Tumor lesions smaller than 1 cm or larger than 4 cm in greatest diameter
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tisch Hospital
New York, New York, United States, 10016
Actively Recruiting
Research Team
T
Tamas A. Gonda, MD
CONTACT
E
Emil Agarunov
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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