Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07307248

To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage

Led by Asian Institute of Gastroenterology, India · Updated on 2026-01-28

408

Participants Needed

1

Research Sites

157 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In adults with walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound (EUS)-guided transluminal necrosectomy, does early removal of the lumen-apposing metal stent (LAMS) (at 2 weeks or immediately after the last necrosectomy) with placement of a double-pigtail plastic stent (DPT), compared to delayed LAMS removal at 4 weeks without a DPT, result in a lower rate of pancreatic fluid collection (PFC) recurrence or need for reintervention over 12 months.

CONDITIONS

Official Title

To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of walled-off pancreatic necrosis (WON) undergoing endoscopic ultrasound-guided drainage with lumen-apposing metal stent (LAMS)
  • At least 70% resolution of pancreatic fluid collection on CT or MRI at 2 weeks after initial drainage
Not Eligible

You will not qualify if you...

  • Having chronic pancreatitis
  • Suspected or confirmed pancreatic cancer
  • Incomplete endoscopic necrosectomy or large necrotic debris remaining on imaging at 2 weeks
  • Major complications within 2 weeks after drainage, such as significant bleeding, infection needing intervention, or stent migration
  • Unable or unwilling to give written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Asian Institute of Gastroenterology

Hyderabad, Telangana, India, 500082

Actively Recruiting

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Research Team

D

Deepak L JHA, DrNB( medical gastroenterology

CONTACT

N

Nitin G Jagtap, DNB (Medical Gastroenterology)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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