Actively Recruiting

Early Phase 1
Age: 18Years - 70Years
All Genders
NCT05610956

Evaluate the Possible Efficacy and Safety of Empagliflozin in Patient With Ulcerative Colitis

Led by Tanta University · Updated on 2025-07-16

60

Participants Needed

1

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

•This study will be a randomized, controlled, parallel study. .To demonstrate the efficacy of empagliflozin and clinical improvement in patients of mild to moderate UC using the Montreal classification of severity of ulcerative colitis.

CONDITIONS

Official Title

Evaluate the Possible Efficacy and Safety of Empagliflozin in Patient With Ulcerative Colitis

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with mild to moderate ulcerative colitis diagnosed by history and clinical signs according to the Montreal classification
  • Diagnosis confirmed by endoscopy and biopsy to establish chronic inflammation and exclude other causes of colitis
  • Age between 18 and 70 years
Not Eligible

You will not qualify if you...

  • Other inflammatory bowel diseases such as Crohn's disease
  • History of serious hypersensitivity to empagliflozin or any component of the medication
  • Patients undergoing dialysis
  • Severe kidney impairment with eGFR less than 20 ml/min/1.73m2
  • Chronic urinary tract infection
  • Chronic genital infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Gastroenterology and Endoscopy Unit, Internal Medicine Department, Tanta University Hospital.

Tanta, Egypt

Actively Recruiting

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Research Team

Y

youmna H eldeeb, phD

CONTACT

S

Sahar M Elhaggar

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Evaluate the Possible Efficacy and Safety of Empagliflozin in Patient With Ulcerative Colitis | DecenTrialz