Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
NCT07311369

Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Pain Management in Abdominal Surgery

Led by Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. · Updated on 2025-12-30

40

Participants Needed

1

Research Sites

12 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a multiple-center, randomized, double-blind, placebo-controlled study design evaluating the safety, efficacy, and pharmacokinetics (PK) parameter of HL-1186 tablet for postoperative pain management in abdominal surgery.

CONDITIONS

Official Title

Evaluate the Safety and Efficacy of HL-1186 Tablet for Postoperative Pain Management in Abdominal Surgery

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years
  • Body Mass Index (BMI) between 18 and 30 kg/m2
  • Scheduled to undergo abdominal surgery under general anesthesia
  • Able to understand the study process, use pain scales, and communicate effectively
Not Eligible

You will not qualify if you...

  • Previous surgery at the same site that may affect pain perception
  • Allergy to any component of the study drug, anesthetic, analgesic, antiemetic agents, or three or more substances
  • Unstable angina, recent myocardial infarction, severe arrhythmias, NYHA class III or higher cardiac function, or recurrent asthma within screening period
  • High bleeding risk conditions such as congenital bleeding disorders, platelet function abnormalities, or active bleeding
  • Pregnant or breastfeeding women within 1 year postpartum
  • Planning conception, sperm/egg donation within 6 months post-treatment, or unwilling to use effective contraception
  • Any other conditions deemed unsuitable by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Third Xiangya Hospital of Central South University

Changsha, Hunan, China

Actively Recruiting

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Research Team

R

Renhai Yang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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