Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06158087

To Evaluate the Safety and Efficacy of Intracranial Stent Assisted Endovascular Treatment of Intracranial Aneurysms

Led by Shanghai Wallaby Medical Technologies Co.,Inc. · Updated on 2024-06-27

130

Participants Needed

1

Research Sites

129 weeks

Total Duration

On this page

Sponsors

S

Shanghai Wallaby Medical Technologies Co.,Inc.

Lead Sponsor

P

Phenox GmbH

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to assess safety and effectiveness of the pEGASUS stent system.

CONDITIONS

Official Title

To Evaluate the Safety and Efficacy of Intracranial Stent Assisted Endovascular Treatment of Intracranial Aneurysms

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged from 18 to 80 years, male or female
  • Diagnosed with wide-neck intracranial aneurysms by brain CTA, MRA, or DSA (neck width 64 mm or dome-to-neck ratio < 2)
  • Parent vessel diameter between 2.5 mm and 4.5 mm
  • Target aneurysm planned for embolization using intracranial stent assisted coiling
  • Modified Rankin Scale (mRS) score of 0 to 2
  • Understand study purpose, accept follow-up, agree to participate and sign informed consent
Not Eligible

You will not qualify if you...

  • Contraindication to antiplatelet or anticoagulant therapy or failure to start antiplatelet therapy before treatment
  • Anatomical unsuitability for endovascular treatment due to severe vascular tortuosity or stenosis
  • Known allergy to Nitinol platinum alloy or angiographic agents
  • Conditions preventing study completion (e.g., expected survival < 1 year, high-risk cerebral thrombosis, heart failure, atrial fibrillation)
  • Presence of moyamoya disease, intracranial tumor, arteriovenous malformation, fistula, or hematoma
  • Previous intravascular embolization or stent treatment of target aneurysm
  • Multiple or complex aneurysms
  • Acute ruptured aneurysm
  • Uncontrolled serious infection
  • Major surgery or interventional therapy within 30 days before study
  • Abnormal coagulation or bleeding tendency
  • Severe renal insufficiency (creatinine 6 200 umol/L) or severe liver disease
  • Pregnancy, lactation, or planning pregnancy during study
  • Participation in another clinical trial within 30 days before consent
  • Other conditions considered unsuitable by investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Changhai Hospital

Shanghai, Shanghai Municipality, China, 222018

Actively Recruiting

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Research Team

W

Wenwen Jia

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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