Actively Recruiting
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
Led by Smita De · Updated on 2025-09-22
50
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy. Holmium laser enucleation of the prostate (HoLEP) was the earliest form of prostate enucleation and is recommended by the American Urological Association (AUA), along with thulium laser enucleation of the prostate (ThuLEP), as size-independent techniques for the management of BPH with fewer complications than transurethral resection of the prostate (TURP). Further development of laser technology has additionally led to enucleation using pulsed-modulated (e.g. "Virtual Basket™" mode or MOSES™ mode) holmium lasers as well as the thulium fiber laser.
CONDITIONS
Official Title
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Understand and voluntarily sign an informed consent form.
- Male patients with a prostate, at least 18 years of age.
- No prior prostate surgery.
You will not qualify if you...
- Unable or refuse to provide informed consent.
- Prior prostate surgery.
- Bladder stones requiring lasering (small stones removable whole are allowed).
- Unable to stop anticoagulants or antiplatelets as required for surgery and up to 1 week after surgery.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cleveland Clinic Main
Cleveland, Ohio, United States, 44195
Actively Recruiting
Research Team
I
Iva Markovic
CONTACT
S
Smita De, MD, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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