Study of Crosslinked Hyaluronate Canalicular Gel for Treating Dry Eye Disease in Adults Undergoing Cataract Surgery with Advanced Lens Implants

What this Trial Is About

This research aims to evaluate how patients respond to a special gel called crosslinked hyaluronate canalicular gel used to treat dry eye disease in those undergoing cataract surgery with advanced lens implants. The study is prospective and will take place at a single site, enrolling 60 patients who have dry eye disease and have chosen advanced intraocular lens implantation during their cataract procedure. Participants will receive the gel applied to both eyes before surgery to block tear drainage canals, which may help with dry eye symptoms. The study includes five visits over a period of 3 to 5 months. This is a single-arm study, meaning all participants receive the gel treatment, and there is no comparison group. During the study, patients will attend scheduled visits for assessments, including measuring tear stability using a non-invasive ocular surface analyzer. The primary outcome is the change in tear break-up time from baseline to three months after treatment. Researchers will monitor participants throughout the study to understand the gels effects on dry eye disease in the context of cataract surgery.

Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery