Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05157113

Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

Led by University of California, San Francisco · Updated on 2025-07-23

70

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to replace this complex regimen with a single administration of intraocular antibiotic and subconjunctival steroid at the time of surgery. This pilot study will obtain the preliminary data required to eventually fully evaluate this innovation in postoperative care in a safety-net population with respect to postoperative outcomes, patient compliance, and patient and caregiver satisfaction.

CONDITIONS

Official Title

Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients initially seen at Zuckerberg San Francisco General Hospital eye clinic and approved for cataract surgery in both eyes
  • Patients 18 years of age or older
  • Patients who choose to have cataract surgery in both eyes
Not Eligible

You will not qualify if you...

  • Patients needing cataract surgery in both eyes on the same day
  • History of endophthalmitis, advanced glaucoma, steroid-related eye pressure increase, prior eye surgery, or recent retinal swelling
  • Allergy or intolerance to penicillin or cephalosporin antibiotics
  • Patients needing combined cataract and other eye specialty surgery on the same day
  • Pregnant or breastfeeding patients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG)

San Francisco, California, United States, 94110

Actively Recruiting

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Research Team

S

Sriranjani Padmanabhan, MD

CONTACT

N

Nicole Xin, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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