Actively Recruiting
Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Led by Envivo Bio Inc · Updated on 2025-06-11
34
Participants Needed
1
Research Sites
106 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
We will sample intestinal microbiota using a microbiome sampling capsule in patients with Small Intestinal Bacterial Overgrowth (SIBO)
CONDITIONS
Official Title
Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males or females aged 18 to 80 years at the first Screening Visit
- ASA Classification 1 or 2
- Women of childbearing potential must have a negative urine pregnancy test within 7 days of Screening Visit
- Willingness to use highly effective contraception during the entire study period (e.g., implants, injectables, oral contraceptives, intra-uterine device, or abstinence)
- Fluent in English, understands the study protocol and informed consent, and willing and able to comply with study requirements
- Positive for at least one clinical symptom consistent with SIBO
- Positive lactulose breath test for SIBO by Hydrogen (H2) criteria
- Prescribed but not yet started a two-week course of rifaximin for SIBO
You will not qualify if you...
- History of prior gastric or esophageal surgery, including lap banding or bariatric surgery
- History of bowel obstruction, gastric outlet obstruction, diverticulitis, inflammatory bowel disease
- History of ileostomy or colostomy
- History of gastric or esophageal cancer, achalasia, esophageal diverticulum
- Active dysphagia or odynophagia
- Taking proton-pump-inhibitor medication within 30 days of enrollment
- Pregnancy, planned pregnancy within 30 days from Screening Visit, or breastfeeding
- Active substance abuse or dependence (including drug or alcohol abuse)
- Unstable medical or psychiatric disorder
- Any chronic condition that could interfere with study conduct or pose health risk as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Silicon Valley Gastroenterology
Mountain View, California, United States, 94040
Actively Recruiting
Research Team
J
Jennifer Taufui
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here