Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06665204

Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain

Led by Sara Gorczynski, PT, DPT · Updated on 2026-05-06

440

Participants Needed

1

Research Sites

162 weeks

Total Duration

On this page

Sponsors

S

Sara Gorczynski, PT, DPT

Lead Sponsor

B

Brooke Army Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The overall goal of this multisite, randomized clinical trial is to evaluate the short- and long-term effectiveness of a Clinical Practice Guideline (CPG)-adherent physical therapy approach to patellofemoral pain (PFP) management among military Service members. The main questions it aims to answer are: 1. Can a CPG-adherent care approach to PFP management improve short- and long-term knee function, pain, and confidence with completing duty-related activities? 2. Can a CPG-adherent care approach to PFP management reduce utilization of healthcare resources and analgesic medication prescription at 12-month follow-up? 3. Are there patient- and care-specific factors that predict or mediate clinical benefit from physical therapy care for PFP? Researchers will compare the CPG-adherent physical therapy intervention to usual physical therapy care in the Military Health System. Participants will: 1) be randomized to receive CPG-adherent care or usual care for PFP management; 2) attend physical therapy corresponding to their group assignment; and 3) complete patient-reported outcome measures at baseline and 6-weeks and 3-, 6-, and 12-months post-randomization.

CONDITIONS

Official Title

Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Active-duty Service member
  • Aged 618 years
  • Unilateral or bilateral patellofemoral pain with pain reproduced by at least one activity loading the patellofemoral joint during weight bearing on a flexed knee (e.g., prolonged sitting, kneeling, squatting, hopping, running, stair climbing, patellar palpation)
  • Available to participate in physical therapy treatment within 6 weeks of enrollment
Not Eligible

You will not qualify if you...

  • Tibiofemoral osteoarthritis based on imaging or self-report within the past year
  • History of patellar or intra-articular knee trauma (e.g., dislocation, fracture) or surgery
  • History of neurodegenerative conditions affecting movement (e.g., Multiple Sclerosis)
  • Meniscal or ligament injuries within the past year based on imaging or self-report
  • Quadriceps or patellar tendon injuries within the past year based on imaging or self-report
  • Known pregnancy (pregnant females may participate after pregnancy ends and with medical clearance)
  • Receipt of physical therapy for patellofemoral pain within 3 months prior to enrollment
  • Pending medical evaluation board, scheduled discharge, deployment, or litigation for an injury at enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Naval Medical Center San Diego

San Diego, California, United States, 92134

Actively Recruiting

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Research Team

S

Sara R Gorczynski, PT, DPT

CONTACT

S

Shanmugasundaram Natesan, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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