Testing an Online Therapy Program iCARE to Reduce Symptoms of Postpartum Depression in Mothers

What this Trial Is About

Postpartum depression PPD is a common and serious condition affecting women after childbirth, characterized by symptoms like low mood, loss of interest, and impaired functioning. This trial evaluates whether adding an internet-based cognitive behavioral therapy iCBT program with Acceptance and Commitment Therapy ACT elements, called iCARE, to usual treatment can better reduce depressive symptoms in mothers with PPD in Denmark. The study also includes a qualitative process evaluation to understand participant experiences and factors affecting the interventions impact. The iCARE program is a self-guided online therapy consisting of four core modules focused on self-care, mindfulness, self-compassion, positive experiences, and challenging negative thinking. Four optional modules offer additional support for presence, communication, bonding with the baby, and coping with difficult thoughts. Participants are randomly assigned to receive either iCARE alongside treatment as usual TAU or TAU alone. TAU varies by municipality and may include psychological support, follow-up by health nurses, general practitioner visits, antidepressants, or private psychologist services. Women in the study will be assessed at baseline, 2 months, and 6 months for postpartum depression symptoms, anxiety, health-related functioning, negative thoughts, and parental stress. Researchers will collect data through questionnaires and evaluate how well participants engage with the program. The total duration of participation covers these timepoints, with safety and acceptability monitored throughout. This approach aims to provide flexible, accessible support for mothers facing PPD.

Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression