Actively Recruiting

Age: 18Years - 80Years
All Genders
ID06719232

Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation: a Prospective Observational Study

Led by Jahn Ferenc South Pest Teaching Hospital · Updated on 2024-12-12

300

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate a catheter-free method for delivering medications directly into the bladder, called intravesical instillation. This method is commonly used for conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS), recurrent urinary tract infections, bladder cancer, and post-chemotherapy or post-radiation cystitis. The study investigates whether this approach reduces discomfort and complications while maintaining treatment effectiveness compared to traditional catheter-based methods. The treatment involves using a specialized urological adapter called UroDapter, which attaches to a syringe and is inserted about 6-8 mm into the urethral opening. This allows medication to reach the bladder without catheterization, aiming to minimize pain, discomfort, and risks like urinary tract infections and urethral damage. Patients receive catheter-free intravesical instillation therapy as their physicians recommend, covering various bladder conditions. Participants will be monitored for up to two weeks to assess patient discomfort during the catheter-free instillation. Researchers will also track success rates of the procedure, incidence of urinary tract infections, urethral bleeding, other complications, and patient preference for this method. Data will be collected anonymously to improve treatment protocols, patient satisfaction, and compliance with intravesical therapies.

CONDITIONS

Brief Title

Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients aged between 18 and 80 years
  • Patients requiring intravesical instillation for interstitial cystitis/bladder pain syndrome (IC/BPS), recurrent urinary tract infections (UTIs), non-muscle invasive bladder cancer, post-radiation cystitis, or post-chemotherapy cystitis
  • Negative urine culture within the last two weeks
  • Provided verbal and written informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Urinary tract infection within the past month or currently active infection
  • Diagnosed bleeding disorders or recurrent visible blood in urine
  • Post-void residual urine volume greater than 100 ml
  • Mental condition that prevents reliable cooperation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Up to two weeks

Participants receive catheter-free intravesical instillations using a specialized urological adapter inserted 6-8 mm into the urethral opening to deliver treatment directly into the bladder without catheterization.

Multiple instillation visits over up to two weeks

Follow-up

Duration - Up to 2 weeks following the last instillation

Participants are monitored for complications such as urinary tract infections, urethral bleeding, and other post-treatment issues, as well as patient preference and treatment success.

Approximately 1 to 2 follow-up visits

Trial Site Locations

Total: 2 locations

1

Military Hospital Medical Centre, Hungarian Defense Forces

Budapest, Hungary, 1134

Actively Recruiting

2

Jahn Ferenc South-Pest Hospital

Budapest, Hungary, 1204

Actively Recruiting

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Research Team

Z

Zoltan Balogh, Dr.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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