Study of Combined Traditional Chinese and Western Medicine for Ankylosing Spondylitis Evaluating Short-Term Functional Improvement and Prognosis in Adults

What this Trial Is About

Researchers are evaluating the clinical effectiveness of combining Traditional Chinese and Western Medicine to improve short-term function in patients with ankylosing spondylitis. This multicenter, prospective cohort study focuses on measuring functional improvement using the Bath Ankylosing Spondylitis Functional Index BASFI after 6 months of treatment. Participants are divided into two groups those receiving integrated Traditional Chinese and Western Medicine therapy and those receiving only Western medicine during the follow-up period. The study includes multiple assessments at baseline and at intervals up to 24 months, monitoring disease activity, quality of life, pain levels, inflammation markers, medication adherence, and adverse events. During the study, participants undergo regular evaluations including the BASFI, Bath Ankylosing Spondylitis Disease Activity Index BASDAI, Ankylosing Spondylitis Disease Activity Score based on C-reactive protein, and other scales related to mobility and quality of life. Blood tests, pain scores, and medication use are tracked to understand treatment effects and safety over two years. The primary outcome is functional improvement at 6 months, with continued monitoring through 24 months.

Evaluating the Efficacy and Short-Term Prognosis of Integrated Traditional Chinese and Western Medicine for Ankylosing Spondylitis(AS): A Protocol for a Cohort Study