Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06939959

Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.

Led by Khyber Teaching Hospital · Updated on 2025-04-23

126

Participants Needed

1

Research Sites

53 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a parallel randomized controlled trial for the treatment of dry eye disease. The main objective is to investigate the efficacy and safety of the use of insulin eye drops in the control of moderate-severe dry eye disease. Topical insulin drops will be compared to artificial tears in improving the ocular surface interface in patients with dry eye disease over 1 year period.

CONDITIONS

Official Title

Evaluating the Efficacy of Topical Insulin for the Restoration of Ocular Surface Interface in Dry Eye Disease.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with Schirmer's test less than 10mm after 5 minutes and tear breakup time less than 10 seconds
  • Ocular Surface Disease Index (OSDI) score greater than 32 indicating dry eye disease
  • Any gender
  • Age 18 years and older
Not Eligible

You will not qualify if you...

  • Active ocular infection or severe ocular surface disease other than dry eye disease
  • Eye surgery within the past 6 months
  • Under 18 years old

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Khyber Teaching Hospital

Peshawar, Khyber Pukhtunkhwa, Pakistan, 25000

Actively Recruiting

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Research Team

S

Shafiq Tanveer, MBBS, FCPS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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