Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06871293

Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19

Led by Fundación Cardioinfantil Instituto de Cardiología · Updated on 2026-04-13

374

Participants Needed

1

Research Sites

61 weeks

Total Duration

On this page

Sponsors

F

Fundación Cardioinfantil Instituto de Cardiología

Lead Sponsor

H

Hospital Militar Central, Colombia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to evaluate the impact of a functional and cognitive rehabilitation strategy compared to evidence-based informational messages, on functional capacity, cognitive abilities, quality of life, and disease progression in adults with chronic non-communicable diseases (NCDs) and Long Covid-19. Researchers will compare a structured rehabilitation program to informational support through evidence-based messages to determine if rehabilitation leads to better functional and cognitive outcomes in patients with Long Covid-19. Participants will be randomly assigned to one of two groups: 1. Functional and cognitive rehabilitation: Attending weekly in-person sessions for 8 weeks, including supervised physical and cognitive exercises. 2. Informational support: Receiving weekly evidence-based educational messages for 8 weeks. Participants will undergo assessments at baseline, post-intervention, and six months later, including a six-minute walk test, handgrip strength measurement, and questionnaires on disability, anxiety, depression, fatigue, dyspnea, cognitive function, and quality of life.

CONDITIONS

Official Title

Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of Covid-19.
  • History of arterial hypertension or diabetes mellitus prior to SARS-CoV-2 infection.
  • Presence of two or more concurrent symptoms related to prolonged Covid-19 lasting at least 4 weeks.
  • At least one symptom impacts daily activities, including physical or neuropsychiatric symptoms.
  • Symptoms not explained by pre-existing conditions.
  • Ability to read and participate in in-person rehabilitation sessions or receive informational messages.
Not Eligible

You will not qualify if you...

  • Age over 80 years.
  • Severely advanced medical conditions prior to SARS-CoV-2 infection.
  • Chronic respiratory disease requiring supplemental oxygen.
  • Heart failure with left ventricular ejection fraction less than 40%.
  • Advanced kidney disease with glomerular filtration rate below 30.
  • Two hospitalizations in the year before registry admission for underlying disease.
  • Dependence on a caregiver.
  • Orthopedic or cardiopulmonary conditions preventing aerobic exercise.
  • Neuropsychiatric or cognitive impairments limiting understanding or participation in cognitive exercises.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Fundación Cardioinfantil-Instituto de cardiología

Bogotá, Bogotá DC, Colombia, 110131

Actively Recruiting

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Research Team

K

Karen J Moreno, PT MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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