Actively Recruiting
Evaluating Metabolic and Anti-inflammatory Effect of Genistein on Post-myocardial Infarction Patients
Led by National Taiwan University Hospital · Updated on 2025-08-07
73
Participants Needed
1
Research Sites
117 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if genistein works to provide a beneficial effect to show lipid lowering effect and anti-inflammatory effects and slow the progression of atherosclerosis in post-myocardial infarction adults. It will also learn about the safety of genistein. The main questions it aims to answer are: Does genistein lower triglyceride in participants? What medical problems do participants have when taking genistein? Researchers will compare the baseline, under treatment and washout period triglyceride, hsCRP to see if genistein works to decrease inflammation. Participants will: Take genistein every day for 3 months with a fixed dose manner. Afterwards, there will be 3 months washout period. Visit the clinic once every month for checkups and tests. Keep a diary of their symptoms.
CONDITIONS
Official Title
Evaluating Metabolic and Anti-inflammatory Effect of Genistein on Post-myocardial Infarction Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Written informed consent
- Age 18 years or older
- History of spontaneous myocardial infarction at least 28 days before recruitment
- High sensitivity C-reactive protein (hsCRP) of 0.1 mg/dL or higher
- Body mass index (BMI) of 27 or greater
You will not qualify if you...
- Pregnant or nursing (lactating) women
- Women of child-bearing potential
- Planned coronary revascularization (PCI or CABG)
- Major non-cardiac surgical or endoscopic procedure within past 6 months
- Symptomatic Class IV heart failure (NYHA)
- Uncontrolled hypertension
- Uncontrolled diabetes
- History or evidence of active tuberculosis infection
- Prior carotid angioplasty, stenting, or carotid atherectomy
- Body mass index (BMI) over 40 kg/m2
- Active cancer under treatment
AI-Screening
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Trial Site Locations
Total: 1 location
1
National Taiwan University Hospital
Taipei, Taiwan, Taiwan, 100
Actively Recruiting
Research Team
C
Cho-Kai Wu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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