Actively Recruiting
Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome
Led by Center For Sight · Updated on 2025-12-22
35
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will evaluate the effect of TRYPTYR in patients with Sjögren's syndrome-related dry eye disease. The goal is to determine whether TRYPTYR can improve symptoms and signs of dry eye in this specific patient population.
CONDITIONS
Official Title
Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults over 18 years old with dry eye disease caused by Sj�f6gren's syndrome diagnosed within the past 2 years
- History of using or wanting artificial tears for dry eye symptoms within the past 2 months
- Unanesthetized Schirmer's Test score of 1 mm or more and less than 10 mm in 5 minutes
- Baseline total Corneal Fluorescein Staining score between 2 and 15 on the National Eye Institute grading scale
You will not qualify if you...
- History of eye surgery within the past 6 months
- Contact lens use in either eye within 7 days before baseline or during the study
- Current topical treatment for less than 3 months or expected changes to treatment during the study
- Use of topical steroid eye medication or varenicline nasal spray within 4 weeks before baseline or during the study
- Use of artificial tears within 2 hours before baseline or study visits
- Allergy to any component of the study drug
- Severe, uncontrolled autoimmune diseases such as rheumatoid arthritis or lupus, especially with severe systemic symptoms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Center For Sight
Venice, Florida, United States, 34285
Actively Recruiting
Research Team
G
Gina Thomas
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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