Actively Recruiting

Phase Not Applicable
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT06826781

Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

Led by Spaulding Rehabilitation Hospital · Updated on 2025-10-27

20

Participants Needed

1

Research Sites

56 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise? Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise. Participants will: * Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.

CONDITIONS

Official Title

Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy individuals between 18 to 30 years old
Not Eligible

You will not qualify if you...

  • History of concussion or brain injury causing loss or change in consciousness or cognition within 24 months
  • High cardiac risk according to American College of Sports Medicine guidelines
  • Currently receiving treatment with cardioactive drugs
  • Unable to stand from a seated position without assistance
  • History of neurologic disorder or neurosurgery
  • Pregnancy
  • Any serious chronic medical or psychiatric disease that may interfere with participation or data quality
  • Unable or unwilling to give informed consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

Spaulding Rehabilitation Hospital

Cambridge, Massachusetts, United States, 02138

Actively Recruiting

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Research Team

J

J. Andrew Taylor, MS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

2

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Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise | DecenTrialz