Actively Recruiting
Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)
Led by Roman Guggenberger · Updated on 2024-08-30
100
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine how effectively bone structures of the human skeleton can be visualized using Deep Learning (DL) augmented Magnetic Resonance Imaging (MRI) in individuals with inflammatory and degenerative joint changes, compared to Computed Tomography (CT). MRI is a technique that operates without the use of X-rays. The main question it aims to answer is: 1. Can DL MRI accurately depict bone structures as well as CT? 2. Can DL MRI be used as an alternative to CT to avoid exposure to X-rays in the future? Researchers will compare DL MRI scans to CT scans to see if DL MRI can effectively replace CT in visualizing bone structures without the use of radiation. Participants will: 1. Undergo MRI scans of their skeletal system that will then be processed using DL. 2. Undergo CT scans of the same body region for comparison purposes.
CONDITIONS
Official Title
Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Referral for a clinically indicated MRI examination of the musculoskeletal system to assess inflammatory and degenerative joint changes.
- Willingness to sign the informed consent form.
- No contraindications for a CT examination (e.g., claustrophobia).
You will not qualify if you...
- No signed informed consent form.
- Patients under 18 years of age.
- Pregnant women.
- The calculated effective dose of the CT examination exceeds 5 mSv.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Zurich
Zurich, Switzerland, 8091
Actively Recruiting
Research Team
C
Carina Obermüller, Dr. med.
CONTACT
R
Roman Guggenberger, PD Prof. Dr. med.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
0
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