Actively Recruiting
Evaluating Residual Congestion at Discharge in Acute Heart Failure Patients
Led by Consorci Sanitari Integral · Updated on 2025-07-18
500
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Treatment of congestion is one of the main goals in patients hospitalized for acute heart failure. Nevertheless, current evidence shows that decongestion is often not achieved and that residual congestion at discharge is strongly associated with poor outcomes. While this association has been demonstrated, previous studies have primarily focused on single parameters of congestion (physical examination, biomarkers, or imaging features). The aim of the study is to assess residual congestion at discharge using a multiparametric approach and to compare the prognostic value of each evaluation strategy. Additionally, the analysis will be supported by artificial intelligence to develop a multiparametric prognostic algorithm that can provide an improved predictive model compared to standard statistical approaches.
CONDITIONS
Official Title
Evaluating Residual Congestion at Discharge in Acute Heart Failure Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 18 years
- Hospitalized for new onset or worsening heart failure
- Symptoms classified as New York Heart Association class III or IV
- Clinical or imaging signs of volume overload such as pulmonary congestion, pitting edema, or jugular venous distension
- Elevated NT-proBNP levels within 24 hours of admission based on age-specific cutoffs
- Ability to provide informed consent
You will not qualify if you...
- Known diagnosis of septicemia
- Glomerular filtration rate less than 15 ml/min
- Life expectancy less than 6 months
- Active myocarditis
- Heart transplant recipients
- Patients with ventricular assist devices
- Congenital heart diseases
- Moderate-to-severe liver disease (Child-Pugh B-C)
- Patients not followed by the Heart Failure Unit
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Complex Hospitalari Universitari Moisès Broggi
Sant Joan Despí, Barcelona, Spain, 08970
Actively Recruiting
Research Team
G
Giosafat Spitaleri, M.D.
CONTACT
R
Roman Freixa, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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