Actively Recruiting

All Genders
Healthy Volunteers
NCT07227116

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

Led by Shady Grove Fertility Reproductive Science Center · Updated on 2025-11-12

280

Participants Needed

12

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the reproductive potential of embryos classified as "complex aneuploid" (involving three or more abnormal chromosomes) or "chaotic" (six or more abnormal chromosomes) through preimplantation genetic testing for aneuploidy (PGT-A). Specifically, we seek to determine whether embryos initially reported as having multiple chromosomal abnormalities might still have the potential for normal chromosomal composition, the opportunity for transfer, and ultimately, the potential to achieve a live birth through re-biopsy and reanalysis. Key Information: This portion of the study seeks your consent for the re-biopsy and genetic reanalysis of the embryos only. It does not yet include consent for potential future transfer. Participation remains completely voluntary, and your decision will not affect your current or future care. We deeply appreciate your support and commitment to advancing fertility research.

CONDITIONS

Official Title

Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Having one or more embryos classified as whole chromosome chaotic or complex aneuploid with three or more chromosomes following preimplantation genetic testing for aneuploidy using an NGS based platform
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Embryos not meeting complex or chaotic criteria
  • Patients declining consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 12 locations

1

IVF Florida Reproductive Associates

Margate, Florida, United States, 33063

Actively Recruiting

2

Shady Grove Fertility

Atlanta, Georgia, United States, 30342

Actively Recruiting

3

Fertility Center of Illinois

Highland Park, Illinois, United States, 60035

Actively Recruiting

4

Shady Grove Fertility

Rockville, Maryland, United States, 20850

Actively Recruiting

5

Shady Grove Fertility

Towson, Maryland, United States, 33607

Actively Recruiting

6

Shady Grove Fertility

Cary, North Carolina, United States, 27519

Actively Recruiting

7

Shady Grove Fertility

Cary, North Carolina, United States, 27519

Actively Recruiting

8

Shady Grove Fertility

Chesterbrook, Pennsylvania, United States, 19087

Actively Recruiting

9

Shady Grove Fertility

Fairfax, Virginia, United States, 22031

Actively Recruiting

10

Shady Grove Fertility

Norfolk, Virginia, United States, 23507

Actively Recruiting

11

Shady Grove Fertility

Richmond, Virginia, United States, 23235

Actively Recruiting

12

SGFertility Chile Medicina Reproductiva

Santiago, Santiago Metropolitan, Chile, 7630000

Actively Recruiting

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Research Team

S

SGF Research Team SGF Research Team

CONTACT

B

Benjamin S Harris, MD, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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