Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06867185

Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Led by Checkpoint Surgical Inc. · Updated on 2026-01-09

60

Participants Needed

5

Research Sites

96 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.

CONDITIONS

Official Title

Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-80 years
  • Candidate for surgical intervention under general anesthesia
  • Require primary nerve injury repair in at least 1 digital nerve
  • Following resection, have a resulting nerve gap of 64 10mm
  • Able to complete tension-free end-to-end direct repair, or repair with a conduit, autograft, or allograft with a length 6415mm
  • Signed and dated informed consent form
Not Eligible

You will not qualify if you...

  • Severe comorbid conditions such as arrhythmia or congestive heart failure preventing surgery under general anesthesia
  • Nerve repair occurring >1 month post-injury
  • Incomplete nerve transection
  • Injury requiring replantation of target digit
  • Injury distal to the distal interphalangeal joint
  • Injury proximal to branching into the proper or common digital nerves
  • Injuries to both digital arteries of an affected digit
  • History of neuropathy, diabetic neuropathy, or any other known neuropathy
  • History of chronic ischemic condition of the upper extremity
  • Cognitive impairment preventing the ability to provide consent, follow post-operative instructions, or complete clinical assessments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Indiana Hand to Shoulder Center

Indianapolis, Indiana, United States, 46260

Actively Recruiting

2

University of Missouri Department of Orthopaedic Surgery

Columbia, Missouri, United States, 65212

Actively Recruiting

3

Washington University in St Louis, Department of Orthopedic Surgery

St Louis, Missouri, United States, 63110

Actively Recruiting

4

The Ohio State Univeristy - Department of Plastic and Reconstructive Surgery

Columbus, Ohio, United States, 43212

Actively Recruiting

5

Harborview Medical Center - University of Washington

Seattle, Washington, United States, 98104

Actively Recruiting

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Research Team

D

Director of Clincal Reseach

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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