Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT06817668

Evaluating Tolerability of ePUHRT With Brachytherapy Boost

Led by Indiana University · Updated on 2025-09-26

31

Participants Needed

1

Research Sites

186 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the tolerability and toxicity of combining two radiation therapy methods for prostate cancer: Elective Pelvic Ultra Hypofractionated Irradiation Treatment (ePUHRT), which is an external beam radiotherapy with High Dose Rate Brachytherapy Boost (form of internal radiation where a cancer doctor implants a small plastic tube or balloon (catheter) in the tumor).

CONDITIONS

Official Title

Evaluating Tolerability of ePUHRT With Brachytherapy Boost

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years old or older at the time of informed consent
  • Able to provide informed consent and HIPAA authorization
  • Karnofsky performance score of 70 or higher
  • Pathologically confirmed unfavorable intermediate, high, or very high-risk prostate cancer
  • Candidate plans to undergo standard prostate high dose brachytherapy boost procedure
Not Eligible

You will not qualify if you...

  • Previous pelvic radiation treatment
  • Prior rectal surgery preventing use of rectal ultrasound probe
  • Evidence of nodal or distant disease on screening diagnostic tests
  • Previous prostate surgery including prostatectomy, Holmium laser enucleation, or transurethral resection
  • International Prostate Symptom Score (IPSS) greater than 16 despite medical therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Indianapolis, Indiana, United States, 46202

Actively Recruiting

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Research Team

O

Omar Ishaq, MD

CONTACT

K

Kathy Lauer, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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